National Institutes of Health

National Institutes of Health

The National Institutes of Health has announced a call for applications for the Multi-Level HIV Prevention Interventions for Individuals at the Highest Risk of HIV Infection.

The objective of this initiative is to further knowledge about how to best reduce the number of new HIV infections in the US through interventions to promote pre-exposure prophylaxis (PrEP), condom use, and HIV testing. This initiative will support research projects that test the effectiveness of multi-level interventions to prevent HIV in high-risk health disparity populations or subgroups in one or more geographic areas with a high rate of new HIV infections.

Specific Areas

Areas of special interest include, but are not limited, to the following:

  • Testing of interventions in multiple geographic hotspots.
  • Use of cluster randomized trials or multi-site quasi-experimental studies.
  • Interventions that include clinician- or healthcare setting-level intervention components to enhance cultural competency, reduce health-care related stigma and discrimination, and increase clinician comfort and willingness to prescribe PrEP.
  • Engagement of community members of the target high-risk health disparity populations or subgroups as investigators, advisors, or peer interventionists.
  • Collaboration with diverse local stakeholders in addition to HIV-prevention service providers, including school systems, school-based student or parent associations, community-based organizations, consumer organizations, and faith-based organizations, to enhance intervention relevance, feasibility, and sustainability.
  • Projects that examine cost-effectiveness of intervention implementation and delivery.


Funding Information


Application budgets are limited to $500,000 direct costs annually, not including consortia F&A.


Eligibility Criteria


  • Higher Education Institutions
    • Public/State Controlled Institutions of Higher Education
    • Private Institutions of Higher Education
  • The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
    • Hispanic-serving Institutions
    • Historically Black Colleges and Universities (HBCUs)
    • Tribally Controlled Colleges and Universities (TCCUs)
    • Alaska Native and Native Hawaiian Serving Institutions
    • Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
  • Nonprofits Other Than Institutions of Higher Education
    • Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
    • Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
  • For-Profit Organizations
    • Small Businesses
    • For-Profit Organizations (Other than Small Businesses)
  • Local Governments
    • State Governments
    • County Governments
    • City or Township Governments
    • Special District Governments
    • Indian/Native American Tribal Governments (Federally Recognized)
    • Indian/Native American Tribal Governments (Other than Federally Recognized)
  • Federal Governments
    • U.S. Territory or Possession
  • Other
    • Independent School Districts
    • Public Housing Authorities/Indian Housing Authorities
    • Native American Tribal Organizations (other than Federally recognized tribal governments)
    • Faith-based or Community-based Organizations
    • Regional Organizations

Post Date - 06-Nov-2020

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